PUBLICATIONS
1. Edar O. Pech-Santiago, Raúl Argüello-García,Citlali Vázquez, Emma Saavedra, Iliana González- Hernández, Helgi Jung-Cook, Steven P. Rafferty, M. Guadalupe Ortega-Pierres. (2022). Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole. PLoS Pathogens. 18(9): e1010840.
2. Brian Cameron Wooding Webb, Steven Rafferty, Andrew James Vreugdenhil. (2022). Preparation and Characterization of Antibacterial Films with Eggshell-Membrane Biopolymers Incorporated with Chitosan and Plant Extracts. Polymers. 14(3): 383. http://dx.doi.org/10.3390/polym14030383
3. Crowley, Erika L., Rafferty, Steven P. (2019). Review of lactose-driven auto-induction expression of isotope-labelled proteins. Protein Expression and Purification. 157: 70-85.
4. Brian Lukaszewicz, Eliza McColl, Janet Yee, Steven Rafferty, Manon Couture. (2017). Resonance-Raman studies on the flavohemoglobin of the protist Giardia intestinalis: evidence of a type I/II-peroxidase-like heme environment and roles of the active site distal residues. Journal of Biological Inorganic Chemistry. 22: 1099-1108.
5. Zhen (Alice) Yang, Robert Pazdzior, Janet Yee, Steven Rafferty. (2016). Reduction potential and heme- pocket polarity in low potential cytochrome b5 of Giardia intestinalis. Journal of Inorganic Biochemistry. 158: 110-114.
6. Robert Pazdzior, Zhen Yan, Mirfath Sultana Mesbahuddin, Janet Yee, Art van der Est, Steven Rafferty. (2015). Low reduction potential cytochrome b5 isotypes of Giardia intestinalis. Experimental Parasitology. 157: 197-201.
7. Steven Patrick Rafferty, Guillem Dayer. (2015). Heme proteins of Giardia intestinalis. Experimental Parasitology. 159: 13-23.
8. Samiah Alam, Janet Yee, Manon Couture, Shin-ichi J. Takayama, Wan-Hsin Tseng, A. Grant Mauk, Steven Rafferty. (2012). Cytochrome b5 from Giardia lamblia. Metallomics. 4(12): 1255-1261.
9. Steven Patrick Rafferty. (2011). Nitric Oxide Synthases of Bacteria – and Other Unicellular Organisms. The Open Nitric Oxide Journal. 3: 25-32.
10. Daniel B Lustig, Cora Kempt, Samiah Alam, James Clancy, Janet Yee, Steven Patrick Rafferty. (2011). Mutation of conserved tryptophan residues at the dimer interface of Staphylococcus aureus nitric oxide synthase. Archives of Biochemistry and Biophysics. 506(2): 165-172.
11. McCarthy SD , Rafferty SP , Frost PC. (2010). Responses of alkaline phosphatase activity to phosphorus stress in Daphnia magna. The Journal of Experimental Biology. 213(2): 256-61.
12. Steven Rafferty, Betty Luu, Raymond E March, Janet Yee. (2010). Giardia lamblia encodes a functional flavohemoglobin. Biochem Biophys Res Commun. 399(3): 347-351.
13. Woodcroft MW , Ellis DA , Rafferty SP , Burns DC , March RE , Stock NL , Trumpour KS , Yee J , Munro K. (2010). Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumulation: the key role of the neutral species. Environmental Toxicology and Chemistry / SETAC. 29(8):1669-77.
14. Lang J , Driscoll D , Gélinas S , Rafferty SP , Couture M. (2009). Trp180 of endothelial NOS and Trp56 of bacterial saNOS modulate sigma bonding of the axial cysteine to the heme. Journal of Inorganic Biochemistry. 103(7):1102-12.
15. Wilson DJ , Rafferty SP , Konermann L. (2005). Kinetic unfolding mechanism of the inducible nitric oxide synthase oxygenase domain determined by time-resolved electrospray mass spectrometry. Biochemistry. 44(7):2276-83.
16. Smith JC , Siu KW , Rafferty SP. (2004). Collisional cooling enhances the ability to observe non-covalent interactions within the inducible nitric oxide synthase oxygenase domain: dimerization, complexation, and dissociation. Journal of the American Society for Mass Spectrometry. 15(5):629-38.
17. McDonald JK , Taylor CM , Rafferty S. (2003). Design, preparation, and characterization of mixed dimers of inducible nitric oxide synthase oxygenase domains.Protein Expression and Purification. 27(1):115-27.
18. Delamere C, Lewars E, Rafferty S. (2002). The bonding of nitrosonium ion to sulfur in models of cytochrome c-type biomolecules: an ab initio computational study. Journal of Molecular Structure (Theochem). 582, 27-38.
19. Hao C , March RE , Croley TR , Smith JC , Rafferty SP. (2001). Electrospray ionization tandem mass spectrometric study of salt cluster ions. Part 1--investigations of alkali metal chloride and sodium salt cluster ions. Journal of Mass Spectrometry : JMS. 36(1):79-96.
20. Wilson DJ , Rafferty SP. (2001). A structural role for tryptophan 188 of inducible nitric oxide synthase.Biochemical and biophysical research communications. 287(1):126-9.
21. Rafferty SP , Boyington JC , Kulansky R , Sun PD , Malech HL. (1999). Stoichiometric arginine binding in the oxygenase domain of inducible nitric oxide synthase requires a single molecule of tetrahydrobiopterin per dimer. Biochemical and Biophysical Research Communications. 257(2):344-7.
22. Yan L , Wang S , Rafferty SP , Wesley RA , Danner RL. (1997). Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells. Blood. 90(3) :1160-7.
23. Weil WM , Linton GF , Whiting-Theobald N , Vowells SJ , Rafferty SP , Li F , Malech HL. (1997). Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer. Blood. 89(5) :1754-61.
24. Hunter CL , Lloyd E , Eltis LD , Rafferty SP , Lee H , Smith M , Mauk AG. (1997). Role of the heme propionates in the interaction of heme with apomyoglobin and apocytochrome b5. Biochemistry. 36(5):1010-7.
25. Rafferty S , Malech HL. (1996). High reductase activity of recombinant NOS2 flavoprotein domain lacking the calmodulin binding regulatory sequence. Biochemical and Biophysical Research Communications. 220(3):1002-7.
26. Rafferty SP , Guillemette JG , Berghuis AM , Smith M , Brayer GD , Mauk AG. (1996). Mechanistic and structural contributions of critical surface and internal residues to cytochrome c electron transfer reactivity. Biochemistry. 35(33):10784-92
27. Domachowske JB , Rafferty SP , Singhania N , Mardiney M , Malech HL. (1996). Nitric oxide alters the expression of gamma-globin, H-ferritin, and transferrin receptor in human K562 cells at the posttranscriptional level. Blood. 88(8):2980-8.
28. Rafferty SP , Domachowske JB , Malech HL. (1996). Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line. Blood. 88(3):1070-8.
29. Krantz A , Spencer RW , Tam TF , Liak TJ , Copp LJ , Thomas EM , Rafferty SP. (1990). Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase. Journal of Medicinal Chemistry. 33(2):464-79.
30. Rafferty SP , Pearce LL , Barker PD , Guillemette JG , Kay CM , Smith M , Mauk AG. (1990). Electrochemical, kinetic, and circular dichroic consequences of mutations at position 82 of yeast iso-1- cytochrome c. Biochemistry. 29(40):9365-9.
1. Edar O. Pech-Santiago, Raúl Argüello-García,Citlali Vázquez, Emma Saavedra, Iliana González- Hernández, Helgi Jung-Cook, Steven P. Rafferty, M. Guadalupe Ortega-Pierres. (2022). Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole. PLoS Pathogens. 18(9): e1010840.
2. Brian Cameron Wooding Webb, Steven Rafferty, Andrew James Vreugdenhil. (2022). Preparation and Characterization of Antibacterial Films with Eggshell-Membrane Biopolymers Incorporated with Chitosan and Plant Extracts. Polymers. 14(3): 383. http://dx.doi.org/10.3390/polym14030383
3. Crowley, Erika L., Rafferty, Steven P. (2019). Review of lactose-driven auto-induction expression of isotope-labelled proteins. Protein Expression and Purification. 157: 70-85.
4. Brian Lukaszewicz, Eliza McColl, Janet Yee, Steven Rafferty, Manon Couture. (2017). Resonance-Raman studies on the flavohemoglobin of the protist Giardia intestinalis: evidence of a type I/II-peroxidase-like heme environment and roles of the active site distal residues. Journal of Biological Inorganic Chemistry. 22: 1099-1108.
5. Zhen (Alice) Yang, Robert Pazdzior, Janet Yee, Steven Rafferty. (2016). Reduction potential and heme- pocket polarity in low potential cytochrome b5 of Giardia intestinalis. Journal of Inorganic Biochemistry. 158: 110-114.
6. Robert Pazdzior, Zhen Yan, Mirfath Sultana Mesbahuddin, Janet Yee, Art van der Est, Steven Rafferty. (2015). Low reduction potential cytochrome b5 isotypes of Giardia intestinalis. Experimental Parasitology. 157: 197-201.
7. Steven Patrick Rafferty, Guillem Dayer. (2015). Heme proteins of Giardia intestinalis. Experimental Parasitology. 159: 13-23.
8. Samiah Alam, Janet Yee, Manon Couture, Shin-ichi J. Takayama, Wan-Hsin Tseng, A. Grant Mauk, Steven Rafferty. (2012). Cytochrome b5 from Giardia lamblia. Metallomics. 4(12): 1255-1261.
9. Steven Patrick Rafferty. (2011). Nitric Oxide Synthases of Bacteria – and Other Unicellular Organisms. The Open Nitric Oxide Journal. 3: 25-32.
10. Daniel B Lustig, Cora Kempt, Samiah Alam, James Clancy, Janet Yee, Steven Patrick Rafferty. (2011). Mutation of conserved tryptophan residues at the dimer interface of Staphylococcus aureus nitric oxide synthase. Archives of Biochemistry and Biophysics. 506(2): 165-172.
11. McCarthy SD , Rafferty SP , Frost PC. (2010). Responses of alkaline phosphatase activity to phosphorus stress in Daphnia magna. The Journal of Experimental Biology. 213(2): 256-61.
12. Steven Rafferty, Betty Luu, Raymond E March, Janet Yee. (2010). Giardia lamblia encodes a functional flavohemoglobin. Biochem Biophys Res Commun. 399(3): 347-351.
13. Woodcroft MW , Ellis DA , Rafferty SP , Burns DC , March RE , Stock NL , Trumpour KS , Yee J , Munro K. (2010). Experimental characterization of the mechanism of perfluorocarboxylic acids' liver protein bioaccumulation: the key role of the neutral species. Environmental Toxicology and Chemistry / SETAC. 29(8):1669-77.
14. Lang J , Driscoll D , Gélinas S , Rafferty SP , Couture M. (2009). Trp180 of endothelial NOS and Trp56 of bacterial saNOS modulate sigma bonding of the axial cysteine to the heme. Journal of Inorganic Biochemistry. 103(7):1102-12.
15. Wilson DJ , Rafferty SP , Konermann L. (2005). Kinetic unfolding mechanism of the inducible nitric oxide synthase oxygenase domain determined by time-resolved electrospray mass spectrometry. Biochemistry. 44(7):2276-83.
16. Smith JC , Siu KW , Rafferty SP. (2004). Collisional cooling enhances the ability to observe non-covalent interactions within the inducible nitric oxide synthase oxygenase domain: dimerization, complexation, and dissociation. Journal of the American Society for Mass Spectrometry. 15(5):629-38.
17. McDonald JK , Taylor CM , Rafferty S. (2003). Design, preparation, and characterization of mixed dimers of inducible nitric oxide synthase oxygenase domains.Protein Expression and Purification. 27(1):115-27.
18. Delamere C, Lewars E, Rafferty S. (2002). The bonding of nitrosonium ion to sulfur in models of cytochrome c-type biomolecules: an ab initio computational study. Journal of Molecular Structure (Theochem). 582, 27-38.
19. Hao C , March RE , Croley TR , Smith JC , Rafferty SP. (2001). Electrospray ionization tandem mass spectrometric study of salt cluster ions. Part 1--investigations of alkali metal chloride and sodium salt cluster ions. Journal of Mass Spectrometry : JMS. 36(1):79-96.
20. Wilson DJ , Rafferty SP. (2001). A structural role for tryptophan 188 of inducible nitric oxide synthase.Biochemical and biophysical research communications. 287(1):126-9.
21. Rafferty SP , Boyington JC , Kulansky R , Sun PD , Malech HL. (1999). Stoichiometric arginine binding in the oxygenase domain of inducible nitric oxide synthase requires a single molecule of tetrahydrobiopterin per dimer. Biochemical and Biophysical Research Communications. 257(2):344-7.
22. Yan L , Wang S , Rafferty SP , Wesley RA , Danner RL. (1997). Endogenously produced nitric oxide increases tumor necrosis factor-alpha production in transfected human U937 cells. Blood. 90(3) :1160-7.
23. Weil WM , Linton GF , Whiting-Theobald N , Vowells SJ , Rafferty SP , Li F , Malech HL. (1997). Genetic correction of p67phox deficient chronic granulomatous disease using peripheral blood progenitor cells as a target for retrovirus mediated gene transfer. Blood. 89(5) :1754-61.
24. Hunter CL , Lloyd E , Eltis LD , Rafferty SP , Lee H , Smith M , Mauk AG. (1997). Role of the heme propionates in the interaction of heme with apomyoglobin and apocytochrome b5. Biochemistry. 36(5):1010-7.
25. Rafferty S , Malech HL. (1996). High reductase activity of recombinant NOS2 flavoprotein domain lacking the calmodulin binding regulatory sequence. Biochemical and Biophysical Research Communications. 220(3):1002-7.
26. Rafferty SP , Guillemette JG , Berghuis AM , Smith M , Brayer GD , Mauk AG. (1996). Mechanistic and structural contributions of critical surface and internal residues to cytochrome c electron transfer reactivity. Biochemistry. 35(33):10784-92
27. Domachowske JB , Rafferty SP , Singhania N , Mardiney M , Malech HL. (1996). Nitric oxide alters the expression of gamma-globin, H-ferritin, and transferrin receptor in human K562 cells at the posttranscriptional level. Blood. 88(8):2980-8.
28. Rafferty SP , Domachowske JB , Malech HL. (1996). Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line. Blood. 88(3):1070-8.
29. Krantz A , Spencer RW , Tam TF , Liak TJ , Copp LJ , Thomas EM , Rafferty SP. (1990). Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase. Journal of Medicinal Chemistry. 33(2):464-79.
30. Rafferty SP , Pearce LL , Barker PD , Guillemette JG , Kay CM , Smith M , Mauk AG. (1990). Electrochemical, kinetic, and circular dichroic consequences of mutations at position 82 of yeast iso-1- cytochrome c. Biochemistry. 29(40):9365-9.